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Post-Herpetic Neuralgias

  • Jan 24
  • 3 min read

What is Post-Herpetic Neuralgia?

Post-herpetic neuralgia (PHN) is a chronic nerve pain condition that can develop following an outbreak of shingles (herpes zoster). Shingles are caused by the reactivation of the varicella-zoster virus, the same virus responsible for chickenpox. While shingles typically resolve within a few weeks, some individuals experience persistent pain in the affected area, known as post-herpetic neuralgia. PHN occurs due to nerve damage caused by the virus and can significantly impact quality of life.


Types of Post-Herpetic Neuralgia

Post-herpetic neuralgia can vary in intensity and presentation. The condition is often categorised based on the type of pain and its duration:

  • Acute Neuralgia: Pain that persists during the shingles outbreak and lasts up to one month after the rash has healed.

  • Subacute Neuralgia: Pain that continues for up to three months following the resolution of the shingles rash.

  • Chronic Post-Herpetic Neuralgia: Pain that lasts for three months or longer, often characterised by nerve-related discomfort and sensitivity in the previously affected area.


Symptoms of Post-Herpetic Neuralgia

The symptoms of PHN can be distressing and vary between individuals. Common symptoms include:

  • Persistent Pain: Burning, stabbing, or aching pain in the area where the shingles rash appeared.

  • Allodynia: Increased sensitivity to touch, where even light contact (such as clothing brushing against the skin) causes pain.

  • Numbness or Tingling: Affected areas may feel numb or experience pins-and-needles sensations.

  • Itching or Irritation: Some individuals report ongoing itchiness or irritation in the affected region.

  • Fatigue and Sleep Disruption: Chronic pain can lead to difficulty sleeping and overall fatigue.


Causes and Risk Factors of Post-Herpetic Neuralgia

PHN is caused by nerve damage resulting from the varicella-zoster virus. The virus affects the nerves during a shingles outbreak, leaving them inflamed and hypersensitive. Certain factors increase the likelihood of developing PHN, including:

  • Age: Individuals over 60 are at a higher risk.

  • Severity of Shingles: A more severe rash and greater nerve involvement increase the risk of PHN.

  • Delayed Treatment: Delays in treating shingles can worsen nerve damage and increase the likelihood of PHN.

  • Weakened Immune System: Conditions that compromise the immune system, such as diabetes or chemotherapy, heighten the risk.


Diagnosis and Treatment Options

Diagnosis: PHN is diagnosed through a combination of medical history and physical examination. Steps include:

  • Medical History and Symptom Assessment: To evaluate the nature, intensity, and duration of the pain.

  • Physical Examination: To identify areas of increased sensitivity, pain, or irritation.

  • Imaging or Nerve Tests: In rare cases, imaging studies or nerve function tests may be used to rule out other conditions.

Treatment: Effective management of post-herpetic neuralgia often involves a combination of approaches tailored to the individual. Options include:

  • Medications:

    • Pain Relievers: Over-the-counter painkillers or prescription opioids for severe cases.

    • Antidepressants: Medications such as amitriptyline or duloxetine help modify pain signals and alleviate nerve pain.

    • Anticonvulsants: Drugs like gabapentin or pregabalin reduce nerve-related pain by calming overactive nerves.

    • Topical Treatments: Lidocaine patches or capsaicin creams provide targeted pain relief.

  • Nerve Block Injections:

    • Local anaesthetic or steroid injections can help reduce pain by interrupting pain signals in the affected nerves.

  • Physical Therapy and Rehabilitation:

    • Tailored exercises to improve mobility and reduce muscle tension associated with chronic pain.

  • Psychological Support:

    • Cognitive behavioural therapy (CBT) or mindfulness techniques can help manage the emotional impact of living with chronic pain.

  • Alternative Therapies:

    • Acupuncture or biofeedback may provide additional pain relief for some individuals.


Prevention of Post-Herpetic Neuralgia

The best way to reduce the risk of PHN is to prevent shingles in the first place. Vaccination against shingles is highly effective and recommended for individuals over 50 or those with weakened immune systems. Early treatment of shingles with antiviral medications, such as acyclovir or valacyclovir, can also help minimise the risk of nerve damage and PHN.


Conclusion

Post-herpetic neuralgia can have a profound impact on an individual’s quality of life, but with appropriate diagnosis and treatment, it is possible to manage symptoms effectively. Early intervention during a shingles outbreak is critical to reducing the risk of developing PHN. If you are experiencing persistent pain following shingles or want to learn more about prevention and treatment, schedule a consultation with us today. Let us help you achieve relief and regain your well-being.

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